PP2C activator, protein serine kinase, phosphorylates RsbS and RsbR, part of the stressosome
function
control of SigB activity
product
PP2C activator, protein serine kinase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]Gene
Coordinates on the chromosome (coding sequence)
520,606 -> 521,007
The protein
Catalyzed reaction/ biological activity
phosphorylation of [protein|621357D1FB6AC1B0499732EFE226F982B26CE34E|RsbR], [protein|F53C527995909A1CFA72C7BF919DD10EE175C6D7|RsbRB], [protein|5EEEDE60CE9E5CDAEBAB0E03AABDF1DF62F1F002|RsbRC], and [protein|979D7A45EAD97C99015029400A85795061BAA367|RsbRD] [Pubmed|21362065]Effectors of protein activity
phosphorylated [protein|621357D1FB6AC1B0499732EFE226F982B26CE34E|RsbR] activates the kinase activity of [protein|ADC52A22950736A0435AEEEC43F7407878786A81|RsbT] [Pubmed|23320651]activity is stimulated by light in a [protein|6C5397BA5839E4DB25B370B39B6DA702147DA8B7|YtvA]-dependent manner [Pubmed|23416074]Structure
[PDB|3VY9] (complete stressosome)Expression and Regulation
[[this]]
Labs working on this gene/protein
[SW|Bill Haldenwang], San Antonio, USA[SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage][SW|Rick Lewis], Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/r.lewis homepage]References
Reviews
19704888,16319496,20658979 Original Articles
8682789,8002610,8682769,9658013,17303566,9786195,15090521,10781545,15583165,8824586,10329124,16321960,8808936,15312768,11244072,15342582,20019076,12499568,12950928,16321960,8955331,18832644,24599254,23407164,23320651,21362065,23416074,21979936,27977677 
